Frans Hochstenbach teaches Metabolic Biochemistry at AUC.
He is assistant professor in the Department of Medical Biochemistry of the Academic Medical Center (AMC) at the University of Amsterdam. He graduated (cum laude) in Biology at Utrecht University with a major in the research group of Prof. Hidde L. Ploegh (Netherlands Cancer Institute, Amsterdam). In 1990, he received his PhD from Leiden University for protein biochemistry on the human gamma-delta T cell receptor in the research group of Prof. Michael B. Brenner (Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA), where he independently identified human calnexin (IP90). Subsequently, he held postdoctoral positions in the research groups of Prof. Ko Okumora (Juntendo University Faculty of Medicine, Tokyo) and Dr. Richard D. Klausner (National Institutes of Health, Bethesda, MD), where he identified the synthase for fungal cell wall alpha-glucan.
In 1996, he returned to the Netherlands with an Academy Fellowship to study cell wall biosynthesis in fission yeast at the Faculty of Science of the University of Amsterdam. In 1999, he joined the Department of Medical Biochemistry in the AMC, where he continued this research on fission yeast, was appointed principal investigator (2008-2014) and supervised the research of four PhD students as 'co-promotor'. Since 2014, he has been working at the AMC as principal educator, in 2017 received his senior education qualification (SKO) from the University of Amsterdam and in 2018 was selected Teacher of the Month by the Board of Directors of the AMC. For the Bachelor’s programme of Medicine of the AMC, he is coordinator Bachelor’s theses, examiner and biochemistry lecturer, and, for the Bachelor’s programme of Biomedical Sciences of the UvA Faculty of Science, he is coordinator Medical Biochemistry and Pathophysiology, examiner and member of the programme committee.